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Objective and subjective rapid frailty screening tools in people with HIV
Author(s) -
Beanland A,
Alagaratnam J,
Goffe C,
Bailey A,
Dosekun O,
Petersen C,
Ayap W,
Garvey LJ,
Walsh J,
Mackie NE,
Winston A
Publication year - 2021
Publication title -
hiv medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.53
H-Index - 79
eISSN - 1468-1293
pISSN - 1464-2662
DOI - 10.1111/hiv.12988
Subject(s) - medicine , polypharmacy , logistic regression , timed up and go test , outpatient clinic , physical therapy , gerontology , balance (ability)
Objectives As people with HIV (PWH) age, the prevalence of frailty increases. Rapid screening tests to identify frailty within HIV outpatient settings are required to identify at‐risk individuals. We undertook a service evaluation to assess three short frailty assessments in PWH. Methods We assessed two objective [gait speed (GS), timed‐up‐and‐go test (TUGT)] and one subjective [the self‐reported health questionnaire (SRH)] frailty screening tools in PWH aged > 40 years attending a single HIV outpatient department. Factors associated with positive frailty screening tests (defined as GS < 0.8 m/s, TUGT ≥ 10 s and SRH score < 6) were assessed using logistic regression models. Ethical considerations This was a service evaluation and was approved as a service evaluation by the Imperial College Healthcare NHS trust HIV clinical research committee (February 2020). All participants were given verbal information and were able to terminate the screening tests at any time. Results Of 84 PWH approached, 80 individuals completed all screening tests (median age = 56 years, range: 40–80) with a positive frailty screening prevalence in 19%, 33% and 20% for GS, TUGT and SRH, respectively. All tests were considered acceptable to participants. Factors statistically significantly associated with frailty included age (GS and TUGT), detectable HIV RNA (TUGT), number of comorbidities (GS and TUGT), presence of polypharmacy (GS and TUGT) and total number of concomitant medication (GS and SRH). Conclusions Rates of positive screening tests for frailty are dependent on screening tool used, with all three tools being acceptable to participants. Objective measures of frailty screening (GS and TUGT) are more closely associated with clinical parameters than is a subjective measure of frailty screening (SRH).