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Acute kidney injury in HIV ‐infected patients: a critical review
Author(s) -
Gameiro J,
Agapito Fonseca J,
Jorge S,
Lopes JA
Publication year - 2019
Publication title -
hiv medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.53
H-Index - 79
eISSN - 1468-1293
pISSN - 1464-2662
DOI - 10.1111/hiv.12685
Subject(s) - medicine , nephrotoxicity , acute kidney injury , intensive care medicine , human immunodeficiency virus (hiv) , incidence (geometry) , renal function , kidney disease , immunology , kidney , physics , optics
Acute kidney injury (AKI) is characterized by a rapid decline of renal function associated with worse outcomes. The purpose of the authors is to perform a critical review of the incidence, risk factors, pathogenesis and outcome of AKI in HIV‐infected patients. Human immunodeficiency virus (HIV)‐infected patients have an increased risk of developing AKI, to which contribute both HIV‐dependent and HIV‐independent factors as well as the nephrotoxicity of drugs used. The increased risk of AKI in HIV‐infected patients and its negative impact on prognosis highlights the need for identification of patients at risk, creation of prevention strategies and management.HIV ‐infected patients have an increased risk of developing AKI , to which both HIV ‐dependent and HIV ‐independent factors contribute, as well as the nephrotoxicity of drugs used. The increased risk of AKI in HIV ‐infected patients and its negative impact on prognosis highlight the need for identification of patients at risk, creation of prevention strategies and management.