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Management of drug interactions with direct‐acting antivirals in Dutch HIV /hepatitis C virus‐coinfected patients: adequate but not perfect
Author(s) -
Smolders EJ,
Smit C,
Kanter CTMM,
Dofferhoff ASM,
Arends JE,
Brinkman K,
Rijnders B,
Valk M,
Reiss P,
Burger DM
Publication year - 2018
Publication title -
hiv medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.53
H-Index - 79
eISSN - 1468-1293
pISSN - 1464-2662
DOI - 10.1111/hiv.12570
Subject(s) - medicine , cart , regimen , coinfection , chronic hepatitis , cohort , hepatitis c virus , hepatitis c , human immunodeficiency virus (hiv) , cohort study , observational study , drug , virus , pharmacology , virology , mechanical engineering , engineering
Direct-acting antivirals (DAAs) for treatment of chronic hepatitis C virus (HCV) infection can cause drug-drug interactions (DDIs) with combination antiretroviral therapy (cART) and non-cART co-medication. We mapped how physicians manage DDIs between DAAs and co-medication and analysed treatment outcomes.