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Ovarian hilar proliferations resembling Sertoli cell tumours: microscopic neoplasms or non‐neoplastic remnants?
Author(s) -
Taylor Jennifer,
Clarke Blaise A,
Hasan Noori U,
Gasljevic Gorana,
Cesari Matthew,
McCluggage W Glenn
Publication year - 2016
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/his.12784
Subject(s) - sertoli cell , pathology , differential diagnosis , biology , immunohistochemistry , medicine , spermatogenesis , endocrinology
Aims To describe four cases of incidentally detected microscopic ovarian hilar Sertoli cell proliferation, a phenomenon that, as far as we are aware, has not been previously reported, and to discuss the differential diagnosis of these lesions. Methods and results The proliferations occurred in women aged 35–62 years, and were composed of solid and hollow tubules that were morphologically and immunohistochemically in keeping with Sertoli cells. Two cases were bilateral. Conclusions We feel that these uncommon proliferations are likely to represent non‐neoplastic embryological remnants rather than hilar Sertoli cell tumours.