Premium
Polypoid stromal lesions of the intestines
Author(s) -
Voltaggio Lysandra,
Montgomery Elizabeth
Publication year - 2015
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/his.12573
Subject(s) - gist , submucosa , muscularis mucosae , mesenchymal stem cell , pathology , inflammatory fibroid polyp , medicine , stromal cell , sarcoma , stromal tumor , mesenchymal tumor , lesion , immunohistochemistry
Interpretation of intestinal mesenchymal lesions is simplified merely by knowing in which anatomic layer they are usually found. For example, Kaposi sarcoma is detected on mucosal biopsies, whereas inflammatory fibroid polyp is almost always in the submucosa. Gastrointestinal stromal tumours ( GIST ) are centred generally in the muscularis propria. Schwannomas are essentially always in the muscularis propria. Knowledge of the favoured layer is also most important in interpreting colon biopsies, as many mesenchymal polyps are encountered in the colon. Herein we discuss several mesenchymal lesions and point out some diagnostic pitfalls.