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Current concepts of colorectal cancer resection pathology
Author(s) -
Nagtegaal Iris D
Publication year - 2015
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1111/his.12563
Subject(s) - multidisciplinary approach , colorectal cancer , medicine , neoadjuvant therapy , resection , medical physics , multidisciplinary team , molecular pathology , intensive care medicine , surgical pathology , cancer , general surgery , computer science , pathology , surgery , nursing , social science , biochemistry , chemistry , sociology , breast cancer , gene
The discussion of pathology results is one of the important items in the multidisciplinary meeting. These results describe not only the adequacy of earlier treatments (neoadjuvant therapy, surgery), but guide subsequent treatment decisions by providing staging information and additional prognostic and predictive factors. In the era of next‐generation sequencing, every so often the emphasis is put on the molecular background of tumours, but the information that can be retrieved from the resection specimen remains essential for optimal patient care. In the current review the different surgical approaches will be described, together with the relevant macroscopic evaluations. Microscopic features will be addressed, giving an overview that is aimed at optimal information exchange in the multidisciplinary meeting. Finally, special requirements for reporting local excisions and specimen after neoadjuvant therapy will be discussed.