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Disseminated carcinomatosis of the bone marrow originating from hepatocellular carcinoma. A case report
Author(s) -
Honda Yohji,
Kawaoka Tomokazu,
Aikata Hiroshi,
Kan Hiromi,
Fujino Hatsue,
Kobayashi Tomoki,
Fukuhara Takayuki,
Naeshiro Noriaki,
Hiramatsu Akira,
Imamura Michio,
Kawakami Yoshiiki,
Hyogo Hideyuki,
Arihiro Koji,
Chayama Kazuaki
Publication year - 2015
Publication title -
hepatology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.123
H-Index - 75
eISSN - 1872-034X
pISSN - 1386-6346
DOI - 10.1111/hepr.12391
Subject(s) - medicine , hepatocellular carcinoma , disseminated intravascular coagulation , autopsy , bone marrow , complication , carcinosis , metastasis , pathology , cancer , peritoneal carcinomatosis , colorectal cancer
A 50‐year‐old male patient was admitted to the hospital for persistent high fever and back pain. He was diagnosed with hepatocellular carcinoma ( HCC ), bone marrow metastasis and disseminated intravascular coagulation ( DIC ). Despite the diagnosis and treatment, the general condition deteriorated rapidly and he died of cerebral hemorrhage associated with generalized bleeding tendency. Autopsy showed multiple HCC in the liver and systemic metastasis including bone marrow. The case describes a rare complication of HCC with disseminated carcinomatosis of the bone marrow ( DCBM ) complicated with DIC , with rapid deterioration and death. This is the first case of DCBM from HCC . Physicians need to be aware of DCBM in patients with HCC .