Premium
Diagnosis of Helicobacter pylori infection
Author(s) -
Bessède Emilie,
Arantes Vitor,
Mégraud Francis,
Coelho Luiz Gonzaga
Publication year - 2017
Publication title -
helicobacter
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 79
eISSN - 1523-5378
pISSN - 1083-4389
DOI - 10.1111/hel.12404
Subject(s) - helicobacter pylori , urea breath test , serology , medicine , helicobacter pylori infection , gastroenterology , gastric mucosa , gastric biopsy , breath test , helicobacter infections , pathology , gastritis , immunology , stomach , antibody
Abstract Important progress is being made in endoscopic methods which allow clinicians to predict the presence of Helicobacter pylori based on characteristics of gastric mucosa and to obtain targeted biopsies. There are also important developments in molecular methods with various techniques derived from standard PCR , applied both on gastric biopsies and stool specimens. Progress is being made in microfluidic systems to get a reliable diagnosis in a very short time. The interest of the 13 C urea breath test has been confirmed as well as stool antigen tests. Attempts are being made to find biological markers of premalignant conditions by serology, other than pepsinogens.