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Gastric Microbiota
Author(s) -
Ianiro Gianluca,
MolinaInfante Javier,
Gasbarrini Antonio
Publication year - 2015
Publication title -
helicobacter
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 79
eISSN - 1523-5378
pISSN - 1083-4389
DOI - 10.1111/hel.12260
Subject(s) - helicobacter pylori , stomach , gastric mucosa , helicobacter infections , human stomach , medicine , biology , gastroenterology
After the discovery of Helicobacter pylori in 1983, the stomach was no longer considered a sterile environment. In 2015, evolving data shows that H. pylori is not the only inhabitant of the gastric mucosa. Using culture‐independent methods of analysis, a non‐ H. pylori microbial community has been recently observed in the human stomach, the so‐called human gastric microbiota, along with H. pylori itself. Increasing evidence supports the hypothesis that although H. pylori may be the most relevant, it is not the only local bacterial culprit leading to gastric diseases. Further studies are warranted to offer a better picture of the role and functions of gastric microbiota and to identify the best therapeutic modulators of gut microbiota for the management of gastric diseases.