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Pathogenesis of Helicobacter pylori Infection
Author(s) -
Bernard Marina,
Josenhans Christine
Publication year - 2014
Publication title -
helicobacter
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 79
eISSN - 1523-5378
pISSN - 1083-4389
DOI - 10.1111/hel.12160
Subject(s) - helicobacter pylori , virulence , pathogenicity island , pathogenesis , colonization , pathogenicity , host (biology) , biology , microbiology and biotechnology , stomach , host factors , immunology , genetics , gene , biochemistry , virus
Helicobacter pylori relies on multiple colonization and virulence factors to persist in the human stomach for life. In addition, these factors can be modulated and vary to suit the ever‐changing environment within the host individual. This article outlines the novel developments in this field of research during the past year, highlighting the cag pathogenicity island, VacA, γ‐glutamyl‐transpeptidase as well as including recent advances in protein structure, bacteria–host interaction, and the role of stomach microbiota.