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From Wakefulness to Sleep: Migraine and Hypnic Headache Association in a Series of 23 Patients
Author(s) -
Ruiz Marina,
Mulero Patricia,
Pedraza María Isabel,
Cruz Carolina,
Rodríguez Cristina,
Muñoz Irene,
Barón Johanna,
Guerrero Angel Luis
Publication year - 2015
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/head.12460
Subject(s) - migraine , headaches , medicine , pediatrics , zolmitriptan , wakefulness , international classification of headache disorders , anesthesia , sumatriptan , psychiatry , electroencephalography , receptor , agonist
Objectives/Background We analyzed characteristics of hypnic headache ( HH ), migraine and the relationship between both headaches in 23 patients. HH is an uncommon primary headache characterized by exclusively sleep‐related attacks. Concurrence of other headaches, mainly migraine, has been reported, but relationship between both syndromes has rarely been considered. Methods We prospectively collected data in a headache outpatient office from J anuary 2008 to S eptember 2013. Demographic data and migraine and hypnic headache mean features were assessed. Results Twenty‐three out of 2500 (0.92%) were diagnosed with HH or probable HH , and 16 of them (69.5%) had a history of migraine. Mean age at onset of HH and migraine was 56.2 ± 9.3 and 24.6 ± 12.2 years, respectively. In 12 cases, migraine attacks disappeared at 56.7 ± 9.8 years old. Regarding the relationship between both syndromes, in 10 patients, migraine disappeared and HH began immediately after. In 1 case there was a pain‐free period, and in 5 an overlap between both headaches was registered. Conclusion A history of migraine is common in HH patients in our series. Most frequent transition pattern was an immediate change between both syndromes. Hypnic headache and migraine might share a common pathophysiological predisposition.