Premium
Vascular Risk in Migraineurs: Interaction of Endothelial and Cortical Excitability Factors
Author(s) -
Murinova Natalia,
Krashin Daniel L.,
Lucas Sylvia
Publication year - 2014
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1111/head.12304
Subject(s) - migraine , cortical spreading depression , aura , medicine , stroke (engine) , migraine with aura , endothelial dysfunction , depression (economics) , risk factor , vascular disease , disease , population , ischemic stroke , cardiology , ischemia , mechanical engineering , environmental health , engineering , economics , macroeconomics
Background Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population. Results There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascular disease and connections between migraine and endothelial, structural, and genetic risk are reviewed. Conclusion There may be an interaction between endothelial dysfunction and cortical spreading depression affecting risk. Patient education and treatment of modifiable risk factors may decrease future vascular events.