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Renal involvement in mushroom poisoning: The case of O rellanus syndrome
Author(s) -
Esposito Pasquale,
La Porta Edoardo,
Calatroni Marta,
Bianzina Stefania,
Libetta Carmelo,
Gregorini Marilena,
Rampino Teresa,
Dal Canton Antonio
Publication year - 2015
Publication title -
hemodialysis international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.658
H-Index - 47
eISSN - 1542-4758
pISSN - 1492-7535
DOI - 10.1111/hdi.12275
Subject(s) - mushroom poisoning , medicine , mushroom , ingestion , renal injury , hemodialysis , interstitial nephritis , toxin , crush syndrome , acute kidney injury , kidney , intensive care medicine , renal replacement therapy , surgery , poison control , food science , emergency medicine , biology , microbiology and biotechnology
Although mushroom poisoning is a rare cause of acute renal injury, in some cases it may lead to the development of a severe and irreversible renal failure. Orellanus syndrome is the most important example of organic renal damage related to mushroom consumption. It is caused by the ingestion of orellanine, the main toxin of different types of C ortinarius mushrooms ( C ortinarius speciosissimus , C . orellanus , C . orellanoides , etc.), and it is characterized by progressive clinical phases with a predominant kidney involvement, finally requiring renal replacement therapy in about 10% of cases. Renal damage is often late and associated with a histological picture of interstitial nephritis. Diagnosis is essentially clinical and no specific therapy has been shown to be effective in preventing and treating renal damage. Here, we describe the case of a patient with mixed wild mushroom poisoning, presenting the typical clinical signs and course of the O rellanus syndrome. This case offers us the opportunity to review the main clinical features of this severe and little‐known intoxication.