Distribution of human single‐nucleotide polymorphisms is approximated by the power law and represents a fractal structure | Zendy

Gouda Norio | Zendy; Shiwa Yuh | Zendy; Akashi Motohiro | Zendy; Yoshikawa Hirofumi | Zendy; Kasahara Ken | Zendy; Furusawa Mitsuru | Zendy

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Distribution of human single‐nucleotide polymorphisms is approximated by the power law and represents a fractal structure

Author(s) -

Gouda Norio,

Shiwa Yuh,

Akashi Motohiro,

Yoshikawa Hirofumi,

Kasahara Ken,

Furusawa Mitsuru

Publication year - 2016

Publication title -

genes to cells

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.912

H-Index - 115

eISSN - 1365-2443

pISSN - 1356-9597

DOI - 10.1111/gtc.12344

Subject(s) - single nucleotide polymorphism , biology , fractal , power law , genetics , distribution (mathematics) , statistical physics , law , computational biology , physics , mathematics , gene , statistics , genotype , mathematical analysis , political science

Single‐nucleotide polymorphisms ( SNP s) are one of the main causes of evolution. The distribution of human SNP s, which were examined in detail genomewide, was analyzed. Three discrete databases of human SNP s were used for this analysis, and similar results were obtained from these databases. It was found that the distribution of the distance between SNP s was approximated by the power law, and the shape of the regions including SNP s had the so‐called fractal structure. Although the reason why the distribution of SNP s obeys such a certain law of physics is unclear, a speculation was attempted in connection with the three‐dimensional structure of human chromatin which has a fractal structure.

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