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Management guideline for Werner syndrome 2020 8. Calcification in tendons associated with Werner syndrome
Author(s) -
Taniguchi Akira,
Tanaka Yasuhito,
Takemoto Minoru,
Kubota Yoshitaka,
Taniguchi Toshibumi,
Motegi Seiichiro,
Nakagami Hironori,
Maezawa Yoshiro,
Koshizaka Masaya,
Kato Hisaya,
Tsukamoto Kazuhisa,
Mori Seijiro,
Kuzuya Masafumi,
Yokote Koutaro
Publication year - 2021
Publication title -
geriatrics and gerontology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 57
eISSN - 1447-0594
pISSN - 1444-1586
DOI - 10.1111/ggi.14084
Subject(s) - medicine , achilles tendon , calcification , werner syndrome , ankle , tendon , foot (prosody) , guideline , surgery , radiology , pathology , helicase , rna , biochemistry , chemistry , linguistics , philosophy , gene
Aim To clarify the diagnostic value of the calcification in the Achilles tendon for Werner syndrome. Methods Calcification of the Achilles tendon in the plain radiograph was investigated in 92 patients with Werner syndrome provided from the nationwide secondary survey in 2010. And the same investigation was performed for 2151 feet in 1853 patients without Werner syndrome, who underwent foot and ankle surgeries at the department of orthopaedic surgery in Nara Medical University from 2004 to 2015. Result and Conclusion Achilles tendon calcification was observed in 70 (76.1%) out of 92 patients with Werner syndrome, whereas that was observed only in 19 feet (0.88%) without Werner syndrome, accompanied by 1 to 4 calcified masses with a maximum diameter ranging from 9.7mm to 63.2mm. The frequency of Achilles tendon calcification in patients with Werner syndrome is far higher than that of patients without Werner syndrome. Achilles tendon calcification could be included in the diagnostic criteria for Werner syndrome. Geriatr Gerontol Int 2021; 21: 163–165 .

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