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Effect of behavioral intervention on medication adherence among elderly with select non‐communicable diseases ( ENDORSE ): Pilot randomized controlled trial
Author(s) -
Raj Jeffrey P,
Mathews Betsy
Publication year - 2020
Publication title -
geriatrics and gerontology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 57
eISSN - 1447-0594
pISSN - 1444-1586
DOI - 10.1111/ggi.14032
Subject(s) - medicine , randomized controlled trial , psychological intervention , pill , intervention (counseling) , non communicable disease , physical therapy , dyslipidemia , diabetes mellitus , disease , psychiatry , nursing , endocrinology
Aim Adherence to medication is important in older patients with non‐communicable diseases, and there is a need to investigate various interventions to enhance adherence in our Indian setting. This pilot randomized controlled trial aimed at testing the effectiveness of systematic education and behavioral intervention in enhancing medication adherence among older adults. Methods It was a single center, open label, parallel arm, randomized controlled trial carried out among older (age >60 years) inpatients of general medicine wards diagnosed with select non‐communicable diseases, such as diabetes, hypertension, dyslipidemia and coronary artery disease. Participants were randomized either to receive the usual standard of care or the intervention that comprises of systematic education, patient diary to mark daily medicine intake and periodic telephone reminders. Barriers to medication adherence were identified and interventions were tailored according to the identified barriers over a 6‐month follow‐up period. The primary end‐points were change in the reported pill count (RPC) within groups and between groups at the third and sixth month. Results The RPC in control and intervention arms at the thrid month were 78.20% and 91.88% ( P = 0.007), whereas at 6 months they were 68.64% and 83.08% ( P = 0.003), respectively. Similarly, change in RPC in intervention arm between baseline and the third month (mean difference 24.08%, P = 0.001), and between baseline and the sixth month (mean difference 15.280%, P = 0.006) were statistically significant. However, the RPC between the third and sixth month showed a significant decline (mean difference 8.8%, P = 0.016). Conclusion In this pilot study, we prove that behavioral interventions have improved medication adherence among older adults, and it is feasible to carry out such studies among older adults in India. Geriatr Gerontol Int 2020; 20: 1079–1084 .