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Correlations between geriatric nutritional risk index and peripheral artery disease in elderly coronary artery disease patients
Author(s) -
Kawamiya Toshiki,
Suzuki Susumu,
Ishii Hideki,
Hirayama Kenshi,
Harada Kazuhiro,
Shibata Yohei,
Tatami Yosuke,
Harata Shingo,
Kawashima Kazuhiro,
Kunimura Ayako,
Takayama Yohei,
Shimbo Yusaku,
Osugi Naohiro,
Yamamoto Dai,
Ota Tomoyuki,
Kono Chikao,
Murohara Toyoaki
Publication year - 2017
Publication title -
geriatrics and gerontology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 57
eISSN - 1447-0594
pISSN - 1444-1586
DOI - 10.1111/ggi.12828
Subject(s) - medicine , odds ratio , coronary artery disease , arterial disease , confidence interval , cardiology , peripheral , disease , multivariate analysis , artery , ankle , vascular disease , surgery
Aim Malnutrition is associated with the development of atherosclerosis and an increased risk of cardiovascular mortality in elderly patients. The present study aimed to investigate the association between the Geriatric Nutritional Risk Index (GNRI), a simple nutritional assessment tool, and the prevalence of peripheral artery disease (PAD) in elderly coronary artery disease patients. Methods We evaluated 228 elderly coronary artery disease patients (mean age 74.0 ± 5.7 years). Ankle‐brachial index (ABI) measurements were routinely carried out to investigate the prevalence of lower extremity PAD. Patients showing ABI <0.9 were defined as having PAD. Results Based on our findings, 20.6% of the study patients had PAD. The median GNRI values were significantly lower in patients with PAD than those in patients without PAD (93.8 vs 100.0, P < 0.001). Even after multivariate adjustment, GNRI values were independently associated with PAD (odds ratio 0.94; 95% confidence interval 0.89–0.99; P = 0.024). Furthermore, patients with low GNRI and high C‐reactive protein levels had a 5.5‐fold higher risk of having PAD than those with high GNRI and low C‐reactive protein levels. Conclusions GNRI values showed a strong relationship with PAD in elderly coronary artery disease patients. These data reinforce the utility of GNRI as a screening tool in clinical practice. Geriatr Gerontol Int 2017; 17: 1057–1062.