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Association of dietary fat intake with the risk of hip fractures in an elderly C hinese population: A matched case–control study
Author(s) -
Zeng Fangfang,
Xie Haili,
Fan Fan,
Xue Wenqiong,
Wu Baohua,
Zhu Huilian,
Chen Yuming
Publication year - 2015
Publication title -
geriatrics and gerontology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 57
eISSN - 1447-0594
pISSN - 1444-1586
DOI - 10.1111/ggi.12417
Subject(s) - medicine , polyunsaturated fatty acid , odds ratio , quartile , confounding , confidence interval , polyunsaturated fat , animal fat , saturated fatty acid , population , saturated fat , physiology , food science , fatty acid , environmental health , cholesterol , biology , biochemistry
Aim The aim of the present study was to examine the association between dietary fat intake and the risk of hip fractures in an elderly C hinese population. Methods A case–control study of 646 patients with newly diagnosed hip fractures and 646 controls, matched by age (±3 years) and sex, was carried out among elderly C hinese (55–80 years) in G uangdong, C hina. Their dietary fat intake was measured and calculated using a 79‐item food‐frequency questionnaire. Results After adjusting for potential confounders, a dose‐dependent increased risk of hip fractures was found to be associated with higher intakes of total fat, animal fat, saturated fatty acids and mono‐unsaturated fatty acids ( P for trend < 0.005). The adjusted odds ratios (95% confidence intervals) for hip fractures from a comparison of extreme quartiles were 1.92 (1.26–2.92) for total fat, 2.60 (1.70–3.99) for animal fat, 1.95 (1.30–2.93) for saturated fatty acids and 2.22 (1.46–3.39) for animal mono‐unsaturated fatty acids, respectively. No significant association was observed for plant fat or polyunsaturated fatty acids ( P for trend = 0.063 for plant fat and 0.174 for polyunsaturated fatty acids). Conclusions Our findings suggest that higher consumption of total fat and animal fat rich in saturated fatty acids might increase the risk of hip fractures in elderly C hinese. Geriatr Gerontol Int 2015; 15: 1171–1178.