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Association between body mass index and cause‐specific mortality as well as hospitalization in frail C hinese older adults
Author(s) -
Chan TuenChing,
Luk James Ka Hay,
Chu LeungWing,
Chan Felix Hon Wai
Publication year - 2015
Publication title -
geriatrics and gerontology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 57
eISSN - 1447-0594
pISSN - 1444-1586
DOI - 10.1111/ggi.12230
Subject(s) - medicine , body mass index , hazard ratio , comorbidity , multivariate analysis , gerontology , cohort study , population , demography , confidence interval , environmental health , sociology
Aim A U ‐shaped relationship between body mass index ( BMI ) and all‐cause mortality has been reported, but there are few studies examining the association between BMI and cause‐specific mortality and hospitalization. We carried out a longitudinal study to examine these associations in C hinese older adults with multiple comorbidities, which could provide a reference for the recommended BMI in this population. Methods From 2004 to 2013, a retrospective cohort of C hinese older adults was selected from a geriatric day hospital in H ong K ong. They were divided into groups according to their BMI : BMI <16; BMI 16–18; BMI 18.1–20; BMI 20.1–22; BMI 22.1–24; BMI 24.1–26; BMI 26.1–28; BMI 28.1–30 and BMI >30. Other assessments included medical, functional, cognitive, social and nutritional assessment. Results A total of 1747 older adults (mean age 80.8 ± 7.1 years, 44.1% male, 46.1% living in nursing homes, C harlson Comorbidity Index 2.0 ± 1.6) with a median follow up of 3.5 years were included. Older adults with BMI 24–28 had the lowest all‐cause, infection‐related and cardiovascular mortality ( P < 0.001). Multivariate analysis showed that there was an inverted J ‐shaped association between BMI and hazard ratio for all‐cause and infection‐related mortality in both nursing home and community‐dwelling older adults. The rate of all‐cause hospitalization was lower in older adults with BMI 22–28 ( P = 0.002). Multivariate analysis showed that there was an inverted J‐shaped association between the odds ratio of recurrent hospitalization and BMI . Conclusion C hinese older adults with BMI 24–28 had lower all‐cause mortality, infection‐related mortality, cardiovascular‐related mortality and all‐cause hospitalization. This study provides a reference for the recommended BMI in this population. Geriatr Gerontol Int 2015; 15 72–79.