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Application of segmental bioelectrical impedance spectroscopy to the assessment of skeletal muscle cell mass in elderly men
Author(s) -
Yamada Yosuke,
Matsuda Kaori,
Björkman Mikko P,
Kimura Misaka
Publication year - 2014
Publication title -
geriatrics and gerontology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 57
eISSN - 1447-0594
pISSN - 1444-1586
DOI - 10.1111/ggi.12212
Subject(s) - bioelectrical impedance analysis , sarcopenia , medicine , skeletal muscle , isometric exercise , extracellular , body water , intracellular , extracellular fluid , muscle atrophy , physical medicine and rehabilitation , physical therapy , cardiology , body mass index , body weight , chemistry , biochemistry
Aim It is important to assess not only the total skeletal muscle mass, but also the intracellular and extracellular compartments of skeletal muscle to examine the actual relationship between skeletal muscle mass and physical functions. Segmental bioelectrical impedance spectroscopy is a unique tool with which to assess intracellular and extracellular water in the limbs. The aim of the present study was to examine the application of segmental bioelectrical impedance spectroscopy to the assessment of skeletal muscle mass in the elderly. Methods A total of 73 healthy elderly men and 20 elderly men requiring care and using an ambulatory day‐care service of the public long‐term care insurance system participated in the present study. The intracellular and extracellular water in the upper and lower legs were assessed by segmental bioelectrical impedance spectroscopy. The gait speed, grip strength and maximal isometric knee extension strength were measured. Results The elderly requiring care had significantly lower intracellular water than did healthy elderly in the upper and lower legs. A significant relative expansion of extracellular water against total water was observed in the elderly requiring care. Receiver operating characteristic curves showed that the area under the curve for the intracellular water index was similar to that for muscle strength in the discrimination of elderly requiring care. Conclusions The elderly requiring care had a relative expansion of extracellular water in the legs, which could have masked actual muscle atrophy. Segmental bioelectrical impedance spectroscopy would be useful for the assessment of skeletal muscle cell mass and sarcopenia in the elderly. Geriatr Gerontol Int 2014; 14 (Suppl. 1): 129–134.