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Association of impaired oral health status with chronic kidney disease in post‐acute rehabilitation
Author(s) -
Shiraishi Ai,
Yoshimura Yoshihiro,
Nagano Fumihiko,
Shimazu Sayuri
Publication year - 2021
Publication title -
gerodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 54
eISSN - 1741-2358
pISSN - 0734-0664
DOI - 10.1111/ger.12527
Subject(s) - medicine , kidney disease , confounding , renal function , logistic regression , rehabilitation , disease , physical therapy
Background Despite the growing interest in oral health and chronic disease in geriatric medicine, the evidence of an association between the two variables is limited. Objectives This study sought to examine the association between oral health status and chronic kidney disease (CKD) in this setting. Materials and methods This retrospective study included consecutive post‐acute patients in a rehabilitation hospital. Oral health status was evaluated using the Revised Oral Assessment Guide (ROAG). Renal function or CKD stage was assessed by measurement of the estimated glomerular filtration rate (eGFR). Multivariate logistic regression analysis was used to determine which subcategories of ROAG were independently associated with advanced CKD stages (vs. early CKD stages). Multiple linear regression analysis was used to clarify whether eGFR on admission was independently associated with ROAG score after adjusting for potential confounders. Results A total of 1056 (mean age 70 years; 52% women) were included in the analysis. Slight and moderate‐to‐severe oral health problems were detected in 57.7% and 15.4% of patients, respectively. Patients with oral problems had a more severe stage of CKD ( P = .036) and a lower eGFR ( P = .028). Among subitems of ROAG, tongue (OR = 1.40, P = .041), saliva (OR = 1.72, P = .039) and oral cavity mucosa (OR = 1.37, P = .013) status was independently associated with the presence of CKD stages 3, 4 and 5. Furthermore, eGFR was independently associated with ROAG score (β = −0.180, P = .034) after adjusting for possible confounders. Conclusions Impaired oral health status is common and closely associated with CKD in post‐acute inpatients.