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Impact of a sodium carbonate spray combined with professional oral hygiene procedures in patients with Sjögren's syndrome: an explorative study
Author(s) -
Gambino Alessio,
Broccoletti Roberto,
Cafaro Adriana,
Cabras Marco,
Carcieri Paola,
Arduino Paolo G.
Publication year - 2017
Publication title -
gerodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 54
eISSN - 1741-2358
pISSN - 0734-0664
DOI - 10.1111/ger.12250
Subject(s) - medicine , oral hygiene , randomized controlled trial , dentistry , saliva , visual analogue scale , sodium bicarbonate , population , physical therapy , chemistry , environmental health
Objectives The aim of this study was to make an initial estimation on the effects of a sodium bicarbonate and xylitol spray (Cariex ® ), associated with non‐surgical periodontal therapy, in participants with primary Sjögren's syndrome. Background Sjögren's syndrome ( SS ) is a multisystem autoimmune disease that predominantly involves salivary and lachrymal glands, with the clinical effect of dry eyes and mouth. Materials and methods A prospective cohort of 22 women and two men has been evaluated. They were randomized into three groups (eight patients each): Group A) those treated once with non‐surgical periodontal therapy, education and motivation to oral hygiene, associated with the use of Cariex ® ; Group B) treated only with Cariex ® ; Group C) treated only with non‐surgical periodontal therapy, education and motivation to oral hygiene. Clinical variables described after treatment were unstimulated whole salivary flow, stimulated whole salivary flow, salivary pH , reported pain (using Visual Analogue Scale) and the Periodontal Screening and Recording index. Results Salivary flow rate improved in all groups, but the difference was statistically significant only in those treated with Cariex ® , alone or in combination with periodontal therapy. Gingival status improved in participants who underwent periodontal non‐surgical therapy while remained unchanged in those only treated with Cariex ® . Reported pain decreased in all groups, showing the best result in participants treated with periodontal therapy together with Cariex ® . Conclusions We propose a practical approach for improving gingival conditions and alleviating oral symptoms in patients with SS . Future randomized and controlled trials are however required to confirm these results as well as larger population, and also assessing other parameters due to oral dryness, possible oral infections and more comprehensive periodontal indices.