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Evaluation of serum calcium and serum parathyroid levels in post‐menopausal women with and without oral dryness
Author(s) -
Singh Balwinder,
Pallagatti Shambulingappa,
Narang Ramandeep Singh,
Kaur Kirandeep,
Sheikh Soheyl,
Manchanda Adesh,
Arora Gagandeep
Publication year - 2016
Publication title -
gerodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 54
eISSN - 1741-2358
pISSN - 0734-0664
DOI - 10.1111/ger.12148
Subject(s) - autoanalyzer , medicine , parathyroid hormone , calcium , endocrinology , menopause , gastroenterology , mann–whitney u test
Objective The primary objective of this study was to estimate and secondary objective was to compare the serum calcium levels and serum parathyroid hormone ( PTH ) levels in post‐menopausal women with and without oral dryness ( OD ). Materials and Methods A case–control study was carried out on 80 selected post‐menopausal women. Salivary flow was assessed by flow rate; serum calcium concentrations were assessed through Semi Autoanalyzer by Arsenazo III reaction. The serum PTH concentration was measured by the enzyme‐linked immunosorbent assay. Severity of OD was assessed by a questionnaire through which the xerostomia inventory ( XI ) score could be measured. Statistical analysis of Student's t ‐test, Mann–Whitney test and Pearson's correlation was used. Results There was a significant difference in mean values of both serum PTH concentration and XI score in post‐menopausal women with/without OD ( p < 0.001). No statistically significant difference ( p = 0.354) was found in salivary flow rate and serum calcium levels in post‐menopausal women in both groups. A positive correlation was found between the serum PTH and XI score in both case and control groups ( p < 0.05). Conclusion Severity of oral dryness in post‐menopausal women is associated with the high levels of serum PTH . However, the correlation of severity of OD with serum calcium could not be established.