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Antimicrobial activity and surface properties of an acrylic resin containing a biocide polymer
Author(s) -
Compagi Marco A.,
Pero Ana C.,
Ramos Stella M. M.,
Marra Juliê,
Paleari André G.,
Rodriguez Larissa S.
Publication year - 2014
Publication title -
gerodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 54
eISSN - 1741-2358
pISSN - 0734-0664
DOI - 10.1111/ger.12031
Subject(s) - acrylic resin , candida albicans , antimicrobial , contact angle , wetting , surface roughness , medicine , nuclear chemistry , adhesion , methacrylate , staphylococcus aureus , polymer , biocide , microbiology and biotechnology , composite material , materials science , bacteria , chemistry , copolymer , biology , genetics , coating , pathology
Objective To evaluate the antimicrobial activity and surface properties of an acrylic resin containing the biocide polymer poly (2‐tert‐butylaminoethyl) methacrylate ( PTBAEMA ). Background Several approaches have been proposed to prevent oral infections, including the incorporation of antimicrobial agents to acrylic resins. Materials and methods Specimens of an acrylic resin (Lucitone 550) were divided into two groups: 0% (control) and 10% PTBAEMA . Antimicrobial activity was assessed by adherence assay of one of the microorganisms, S taphylococcus aureus, S treptococcus mutans and Candida albicans . Surface topography was characterised by atomic force microscopy and wettability properties determined by contact angle measurements. Results Data of viable cells (log (CFU + 1)/ml) for S. aureus (control: 7.9 ± 0.8; 10%: 3.8 ± 3.3) and S. mutans (control: 7.5 ± 0.7; 10%: 5.1 ± 2.7) showed a significant decrease with 10% of PTBAEMA (Mann–Whitney , p < 0.05). For C. albicans (control: 6.6 ± 0.2; 10%: 6.6 ± 0.4), there was no significant difference between control and 10% of PTBAEMA (Kruskal–Wallis, p > 0.05). Incorporating 10% PTBAEMA increased surface roughness and decreased contact angles. Conclusion Incorporating 10% PTBAEMA into acrylic resins increases wettability and roughness of acrylic resin surface; and decreases the adhesion of S. mutans and S. aureus on acrylic surface, but did not exhibit antimicrobial effect against C. albicans .