CDKL5  knockout leads to altered inhibitory transmission in the cerebellum of adult mice | Zendy

Sivilia S. | Zendy; Mangano C. | Zendy; Beggiato S. | Zendy; Giuliani A. | Zendy; Torricella R. | Zendy; Baldassarro V. A. | Zendy; Fernandez M. | Zendy; Lorenzini L. | Zendy; Giardino L. | Zendy; Borelli A. C. | Zendy; Ferraro L. | Zendy; Calzà L. | Zendy

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CDKL5 knockout leads to altered inhibitory transmission in the cerebellum of adult mice

Author(s) -

Sivilia S.,

Mangano C.,

Beggiato S.,

Giuliani A.,

Torricella R.,

Baldassarro V. A.,

Fernandez M.,

Lorenzini L.,

Giardino L.,

Borelli A. C.,

Ferraro L.,

Calzà L.

Publication year - 2016

Publication title -

genes, brain and behavior

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.315

H-Index - 91

eISSN - 1601-183X

pISSN - 1601-1848

DOI - 10.1111/gbb.12292

Subject(s) - cerebellum , glutamatergic , glutamate receptor , excitatory postsynaptic potential , inhibitory postsynaptic potential , motor coordination , gabaergic , knockout mouse , biology , neuroscience , hippocampus , endocrinology , medicine , chemistry , receptor , biochemistry

CDKL5 deletion impairs the establishment of a correct GABA ‐ and glutamatergic cerebellar network, leading to locomotion abnormalities.

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