Open AccessAngiotensin type 1a receptors on corticotropin‐releasing factor neurons contribute to the expression of conditioned fear 1
Author(s) -
Hurt R. C.,
Garrett J. C.,
Keifer O. P.,
Linares A.,
Couling L.,
Speth R. C.,
Ressler K. J.,
Marvar P. J.
Publication year - 2015
Publication title -
genes, brain and behavior
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.315
H-Index - 91
eISSN - 1601-183X
pISSN - 1601-1848
DOI - 10.1111/gbb.12235
Subject(s) - fear conditioning , extinction (optical mineralogy) , receptor , endocrinology , knockout mouse , psychology , population , medicine , neuroscience , amygdala , biology , paleontology , environmental health
Angiotensin II receptor type 1a ( AT 1a R ) and corticotropin‐releasing factor ( CRF ) co‐localize in subsets of paraventricular nucleus ( PVN ) and central amygdala ( CeA ) neurons. Dense AT 1a R and CRF expression is observed in the PVN and CeA of AT 1a R‐GFP (green fluorescent protein) mice.