Optical sensors of heterotrimeric G protein signaling | Zendy

Bondar Alexey | Zendy; Lazar Josef | Zendy

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Optical sensors of heterotrimeric G protein signaling

Author(s) -

Bondar Alexey,

Lazar Josef

Publication year - 2021

Publication title -

the febs journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.981

H-Index - 204

eISSN - 1742-4658

pISSN - 1742-464X

DOI - 10.1111/febs.15655

Subject(s) - heterotrimeric g protein , effector , g protein , g protein coupled receptor , signal transduction , microbiology and biotechnology , function (biology) , signal (programming language) , computational biology , biology , computer science , nanotechnology , materials science , programming language

Heterotrimeric G proteins are central mediators of cellular signal transduction. Our review summarises different approaches towards optical detection of molecular events involved in physiological activity of G proteins, with emphasis on live‐cell imaging techniques. We outline recent advances, as well as identify current challenges and likely future directions of G protein sensor development.

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