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Optical sensors of heterotrimeric G protein signaling
Author(s) -
Bondar Alexey,
Lazar Josef
Publication year - 2021
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.15655
Subject(s) - heterotrimeric g protein , effector , g protein , signal transduction , g protein coupled receptor , microbiology and biotechnology , function (biology) , computational biology , signal (programming language) , biology , protein function , computer science , genetics , gene , programming language
Heterotrimeric G proteins are central mediators of cellular signal transduction. Our review summarises different approaches towards optical detection of molecular events involved in physiological activity of G proteins, with emphasis on live‐cell imaging techniques. We outline recent advances, as well as identify current challenges and likely future directions of G protein sensor development.