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Challenges and possible solutions for decoding extranasal olfactory receptors
Author(s) -
Kalra Siddhant,
Mittal Aayushi,
Bajoria Manisha,
Mishra Tripti,
Maryam Sidrah,
Sengupta Debarka,
Ahuja Gaurav
Publication year - 2021
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.15606
Subject(s) - receptor , biology , computational biology , cell , cell type , olfactory receptor , olfactory system , olfactory epithelium , neuroscience , genetics
The adoption of single‐cell RNA sequencing technologies imparts new means to interrogate the expression of ectopic olfactory receptors at single‐cell resolution. In addition to the quantitative estimation of the cellular transcript, it also offers information about their cell‐type of origin. These and related technologies will spearhead the research on ectopic olfactory receptors, and deconvolute their potential function at the atypical tissue.