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Regulatory roles of circRNAs in adipogenesis and lipid metabolism: emerging insights into lipid‐related diseases
Author(s) -
Chen Chen,
Zhang Xing,
Deng Yuan,
Cui Qingming,
Zhu Ji,
Ren Huibo,
Liu Yingying,
Hu Xionggui,
Zuo Jianbo,
Peng Yinglin
Publication year - 2021
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.15525
Subject(s) - adipogenesis , lipid metabolism , biogenesis , steatosis , biology , adipose tissue , computational biology , lipid metabolism disorder , microrna , bioinformatics , biochemistry , cholesterol , gene , endocrinology , blood lipids
The biogenesis, characteristics, and functional mechanisms of circRNAs are introduced. Then, the methods for circRNA identification and expression profiles of circRNAs associated with adipogenesis and lipid metabolism are summarized. In particular, investigations on the emerging role of circRNAs in regulating adipogenesis and lipid metabolism are reviewed, indicating that circRNAs could be exploited as potential biomarkers for developing powerfully therapeutic strategies against lipid‐related diseases.