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Issue Information
Publication year - 2019
Publication title -
the febs journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.14574
Subject(s) - cover (algebra) , domain (mathematical analysis) , computer science , citation , subject (documents) , information retrieval , library science , mathematics , mechanical engineering , mathematical analysis , engineering
Scribble is a critical regulator of cell polarity, and Scribble interactions with Mutated in Colorectal Cancer (MCC) control the migration of epithelial cells. The image shows immunofluorescence staining using cherry red of endogenous Scribble in MDCK cells grown in collagen in the background. In the foreground the crystal structure of the Scribble PDZ1 domain (steel blue surface) bound to a C‐terminal peptide of MCC (crimson sticks) is shown. For more details see article by Caria et al . in this issue on page 4910‐4925.