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Functions at the junction – membrane proteins and myoblast fusion
Author(s) -
Williamson Patrick
Publication year - 2017
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.14287
Subject(s) - microbiology and biotechnology , fusion mechanism , cell fusion , lipid bilayer fusion , myocyte , multinucleate , cytoplasm , biology , cytoskeleton , cell membrane , syncytium , membrane , cell , chemistry , biochemistry
The fusion of myoblasts is an essential step in the formation of multinucleated muscle fibres and the molecular underpinnings of this process are being actively investigated. In this issue, Kim et al . report that the membrane protein Xkr8 plays a role in myotube fusion, adding another class of membrane proteins to the list of potential contributors to myoblast differentiation and fusion.