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Malaria, metabolism and mathematical models
Author(s) -
Gemayel Rita
Publication year - 2017
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.14161
Subject(s) - malaria , plasmodium falciparum , identification (biology) , computational biology , biology , drug metabolism , glycolysis , cover (algebra) , metabolism , immunology , biochemistry , ecology , engineering , mechanical engineering
Understanding the dynamic behaviour of the Plasmodium falciparum metabolism during infection can help identify targets for drug development. In this Commentary, we highlight recently published studies in The FEBS Journal that cover mathematical modelling of glycolysis in P. falciparum and the identification and in vivo validation of metabolic drug targets.