Autophagy regulates apoptosis on the level of the death‐inducing signalling complex | Zendy

Nowikovsky Karin | Zendy; Bergmann Michael | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Autophagy regulates apoptosis on the level of the death‐inducing signalling complex

Author(s) -

Nowikovsky Karin,

Bergmann Michael

Publication year - 2017

Publication title -

the febs journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.981

H-Index - 204

eISSN - 1742-4658

pISSN - 1742-464X

DOI - 10.1111/febs.14119

Subject(s) - autophagy , microbiology and biotechnology , signal transducing adaptor protein , trif , apoptosis , signalling pathways , signalling , mechanism (biology) , signal transduction , death domain , programmed cell death , chemistry , biology , innate immune system , immune system , immunology , biochemistry , toll like receptor , philosophy , epistemology

The interactions between apoptotic and autophagic proteins via the proteolytic systems are known mechanisms through which autophagy and apoptosis regulate each other. In this issue of The FEBS Journal , Gentle and colleagues propose a mechanism through which autophagy regulates the induction of apoptosis at the level of the TIR‐domain‐containing adaptor‐inducing interferon‐β (TRIF) in TLR signaling.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research