A new class of ribozyme from hepatitis B virus | Zendy

Lim Chun Shen | Zendy; Brown Christopher | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A new class of ribozyme from hepatitis B virus

Author(s) -

Lim Chun Shen,

Brown Christopher

Publication year - 2017

Publication title -

the febs journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.981

H-Index - 204

eISSN - 1742-4658

pISSN - 1742-464X

DOI - 10.1111/febs.14062

Subject(s) - ribozyme , polyadenylation , cleavage (geology) , virology , hepatitis b virus , hairpin ribozyme , biology , virus , microbiology and biotechnology , rna , genetics , gene , paleontology , fracture (geology)

In this issue, Chakraborty and Ghosh present initial in vitro data indicating a 53‐base part of the hepatitis B virus ( HBV ) epsilon region is a ribozyme with unusual properties. Self‐cleavage first occurred at the HBV non‐canonical polyadenylation signal UAUAAA and the “centre bulge” of the epsilon region, releasing a ribozyme. The released ribozyme then acted as a new class of trans‐cleaving ribozyme cleaving other RNA s.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research