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β‐catenin signalling in dermal papilla cells leads to a hairy situation
Author(s) -
Gemayel Rita,
Chenette Emily J.
Publication year - 2016
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.13799
Subject(s) - dermal papillae , microbiology and biotechnology , major duodenal papilla , catenin , signalling , hedgehog signaling pathway , hair loss , regeneration (biology) , mesenchymal stem cell , hair growth , biology , hair follicle , chemistry , anatomy , wnt signaling pathway , signal transduction , physiology , genetics
Dermal papilla (DP) are specialised mesenchymal cells that activate the formation of new hair follicles. In this issue of The FEBS Journal , Zhang and colleagues show that enhancing the β‐catenin signalling pathway in DP cells allows faster and denser hair growth, providing a potential target for hair loss treatments and for improving hair regeneration techniques.