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Novel insights into matrix pathobiology regulatory mechanisms in health and disease
Author(s) -
Karamanos Nikos K.,
Passi Alberto
Publication year - 2014
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.13106
Subject(s) - epigenetics , proteoglycan , epigenesis , computational biology , extracellular matrix , biology , microbiology and biotechnology , matrix (chemical analysis) , neuroscience , bioinformatics , chemistry , biochemistry , dna methylation , gene expression , gene , chromatography
Matrix macromolecules exhibit leading roles in tissue properties, physiological processes, as well as the development and progression of several diseases. This thematic series covers emerging areas of research in the matrix macromolecule field and includes epigenetics, stem cells, micro RNA s, as well as proteoglycan interactions with proteolytic enzymes. Current knowledge of these aspects will elucidate their regulatory mechanisms in pathophysiology and aid the design of novel pharmacological agents. Accompanied by a podcast, listen now . Or listen in iTunes