Premium
Thiamin‐dependent enzymes: new perspectives from the interface between chemistry and biology
Author(s) -
Bunik Victoria I.
Publication year - 2013
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.12589
Subject(s) - enzyme , biochemistry , thiamine , cofactor , chemistry
Accompanied by a podcast, listen now . Or listen in iTunes Identification and enzymological study of the multitude of thiamin (vitamin B1)‐dependent enzymes open new ways to investigate metabolic regulation and disease treatments. The significant contribution of enzymes employing thiamin diphosphate as a coenzyme to solving medical and biotechnological problems is highlighted, together with the currently underestimated role of the enzymes in controlling the levels of the non‐coenzyme thiamin derivatives.