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Fifty‐five years of enzyme classification: advances and difficulties
Author(s) -
McDonald Andrew G.,
Tipton Keith F.
Publication year - 2014
Publication title -
the febs journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.981
H-Index - 204
eISSN - 1742-4658
pISSN - 1742-464X
DOI - 10.1111/febs.12530
Subject(s) - clarity , presentation (obstetrics) , commission , enzyme , subject (documents) , computer science , process (computing) , information retrieval , world wide web , biochemistry , chemistry , political science , medicine , law , surgery , operating system
Since the publication of a list of enzymes classified according to the reactions that they catalysed, by D ixon and W ebb in 1958, its content and presentation have undergone a number of significant changes. These have been necessitated by new information, as well as the need to improve clarity. The move from printed versions to the online environment, through the E xplor E nz website, has allowed the process of adding newly reported enzymes to be automated and the information content to be enriched. Search and output facilities have also been enhanced. These and the problems attendant on the use of the E nzyme C ommission classification system for some groups of enzymes are the subject of this review.