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The pathogenesis of pemphigus: Controversy vs complexity
Author(s) -
Di Zenzo Giovanni,
Borradori Luca,
Muller Eliane J.
Publication year - 2017
Publication title -
experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 96
eISSN - 1600-0625
pISSN - 0906-6705
DOI - 10.1111/exd.13176
Subject(s) - pemphigus , desmoglein , pemphigus vulgaris , pemphigus foliaceus , immunology , pathogenesis , phenotype , desmoglein 3 , desmoglein 1 , epigenetics , dermatology , medicine , biology , gene , antibody , autoantibody , genetics
Life is highly complex and, as quantum physics would predict, follows the rule of "everything is possible with varying probabilities". Accordingly, science may be sometimes as confusing as political debates, where the same matter is addressed in different and misleading ways even in the absence of a real controversy. The Viewpoint by Ahmed et al. provides a paradigmatic example of a debate about two theories for pemphigus pathogenesis, i.e. "Monopathogenic vs. multipathogenic explanations of pemphigus pathophysiology", both being possible but occurring with variable probabilities (1). This article is protected by copyright. All rights reserved