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Light‐independent pro‐inflammatory and pro‐oxidant effects of purified human hair melanins on keratinocyte cell cultures
Author(s) -
Lembo Serena,
Di Caprio Roberta,
Micillo Raffaella,
Balato Anna,
Monfrecola Giuseppe,
Panzella Lucia,
Napolitano Alessandra
Publication year - 2017
Publication title -
experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 96
eISSN - 1600-0625
pISSN - 0906-6705
DOI - 10.1111/exd.13122
Subject(s) - melanin , melanoma , dna damage , carcinogenesis , carcinogen , skin cancer , chemistry , cancer research , microbiology and biotechnology , biology , cancer , dna , biochemistry , genetics , gene
Aim of our study was to test the ability of natural melanins to induce an inflammatory response on cultured keratinocytes and to affect the levels of endogenous antioxidants, independently from light exposure