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Any route for melanoblasts to colonize the skin!
Author(s) -
Petit Valérie,
Larue Lionel
Publication year - 2016
Publication title -
experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 96
eISSN - 1600-0625
pISSN - 0906-6705
DOI - 10.1111/exd.13061
Subject(s) - neural crest , neural tube , biology , embryonic stem cell , anatomy , microbiology and biotechnology , embryo , genetics , gene
Abstract Melanocytes arise from the fourth embryonic layer, the neural crest. They emerge from the roof plate of the neural tube and migrate throughout the body. In mammals, these cells have the capacity to migrate in any type of environment and use various pathways and mechanisms to colonize the skin and hair, and for their maintenance throughout the life of the animal.