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Are itch and scratching the nausea and vomiting of skin?
Author(s) -
Ostadhadi Sattar,
Azimi Ehsan,
Lerner Ethan A.,
Dehpour AhmadReza
Publication year - 2016
Publication title -
experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 96
eISSN - 1600-0625
pISSN - 0906-6705
DOI - 10.1111/exd.12935
Subject(s) - scratching , nausea , vomiting , medicine , dermatology , anesthesia , acoustics , physics
The physiologic similarities between itch and nausea may not be evident initially, but they share the role of repelling irritants and toxins from the body by inducting scratching and vomiting, respectively. In addition, itch and nausea frequently occur together in certain conditions such as uraemia. Here we show that the mechanisms underlying itch and nausea overlap and that advances in either field may influence the identification of novel drug targets, particularly for itch.