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Olopatadine, a non‐sedating H1 antihistamine, decreases the nocturnal scratching without affecting sleep quality in atopic dermatitis
Author(s) -
Yamanaka Keiichi,
Motomura Eishi,
Noro Yuichi,
Umeda Koji,
Morikawa Takuya,
UmedaTogami Kumi,
Omoto Youichi,
Isoda Kenichi,
Kondo Makoto,
Tsuda Kenshiro,
Okuda Masahiro,
Gabazza Esteban C.,
Mizutani Hitoshi
Publication year - 2015
Publication title -
experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 96
eISSN - 1600-0625
pISSN - 0906-6705
DOI - 10.1111/exd.12630
Subject(s) - scratching , antihistamine , atopic dermatitis , medicine , sleep quality , nocturnal , sleep (system call) , dermatology , anesthesia , pharmacology , insomnia , computer science , physics , acoustics , operating system
We have demonstrated for the first time that a second‐generation antihistamine ameliorates nocturnal scratching behavior in atopic dermatitis patients using a modified wristwatch‐type acoustic scratching counting system that we have recently developed. We also analyzed the sleep quality by simultaneous recording of electroencephalogram, and found that sleep quality was unaffected.