TRPV 3: a ‘more than skinny’ channel | Zendy

Nilius Bernd | Zendy; Bíró Tamás | Zendy

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TRPV 3: a ‘more than skinny’ channel

Author(s) -

Nilius Bernd,

Bíró Tamás

Publication year - 2013

Publication title -

experimental dermatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.108

H-Index - 96

eISSN - 1600-0625

pISSN - 0906-6705

DOI - 10.1111/exd.12163

Subject(s) - transient receptor potential channel , trpv , ion channel , skin barrier , trpv4 , trpc1 , trpc5 , chemistry , microbiology and biotechnology , receptor , neuroscience , medicine , biology , trpv1 , dermatology , biochemistry

The skin is our largest organ serving different tasks from barrier formation through somatosensing to hair development. Recently, members of the large trp ( T ransient R eceptor P otential, TRP ) gene family encoding proteins that form cation selective ion channel have been identified to play a crucial role in skin functions. Within the 28 different mammalian TRP channels, TRPV 3 might be the most important member in the skin. This review gives an overview on functional properties of TRPV 3 in skin physiology and in certain skin diseases.

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