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Calcitonin as a potential tumour marker for medullary thyroid carcinoma in an 11‐year‐old Spanish Pure Bred gelding with two independent carcinomas
Author(s) -
Dittus N.,
Hahn K.,
StokarRegenscheit N.,
Gerber V.,
Unger L.
Publication year - 2018
Publication title -
equine veterinary education
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 31
eISSN - 2042-3292
pISSN - 0957-7734
DOI - 10.1111/eve.12744
Subject(s) - medicine , calcitonin , medullary cavity , thyroid , pathology , thyroid carcinoma , medullary carcinoma , adenocarcinoma , carcinoma , biopsy , horse , gastroenterology , cancer , biology , paleontology
Summary An 11‐year‐old Spanish Pure Bred gelding was evaluated for progressive weight loss and exercise intolerance. An ante‐mortem biopsy and post‐mortem histopathological examination of the duodenum revealed a duodenal adenocarcinoma. Furthermore, a medullary thyroid carcinoma of the left thyroid gland and multiple bilateral follicular thyroid adenomas were diagnosed post‐mortem. Serum concentration of calcitonin in this case was markedly increased in comparison to two breed and age matched control horses. This case report shows the rare and independent occurrence of two different types of carcinomas in one horse and highlights the diagnostic value of calcitonin measurements for diagnosis of medullary thyroid carcinoma in horses.