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Successful management of multiple extrapulmonary complications associated with Rhodococcus equi pneumonia in a foal
Author(s) -
Wilkes E. J. A.,
Hughes K. J.,
Kessell A. E.,
Raidal S. L.
Publication year - 2016
Publication title -
equine veterinary education
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 31
eISSN - 2042-3292
pISSN - 0957-7734
DOI - 10.1111/eve.12469
Subject(s) - medicine , rhodococcus equi , foal , pneumonia , clarithromycin , antimicrobial , intensive care medicine , surgery , immunology , organic chemistry , helicobacter pylori , history , biochemistry , chemistry , archaeology , virulence , gene
Summary This report describes the diagnosis and successful treatment of multiple extrapulmonary sequelae of Rhodococcus equi ( R. equi ) pneumonia in a 3‐month‐old filly. Bilateral uveitis and hyphaema, haemolytic anaemia and polysynovitis developed in this foal and were likely due to immune‐mediated mechanisms. The challenges associated with diagnosis and treatments of these extrapulmonary disorders are discussed. The filly was treated initially with clarithromycin and rifampin; however, a blood transfusion and immunosuppressive therapy with dexamethasone were required due to progressive haemolysis and for treatment of uveitis and polysynovitis. Bilateral hyphaema was successfully treated with intracameral injections of a recombinant tissue plasminogen activator. The development of antimicrobial resistance in R. equi was an additional challenge encountered in the management of this case and emphasises the importance of culture and in vitro antimicrobial susceptibility testing of isolates from foals with R. equi pneumonia. Extrapulmonary disorders associated with R. equi pneumonia are likely underdiagnosed and associated with a poor prognosis. This case highlights the importance of thorough and ongoing diagnostic assessment of foals with R. equi pneumonia and demonstrates that a successful outcome can be achieved with appropriate and directed treatment.