Premium
Treatment and resolution of zilpaterol hydrochloride toxicity in a Q uarter H orse gelding
Author(s) -
HepworthWarren K. L.,
Alcott C. J.
Publication year - 2014
Publication title -
equine veterinary education
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 31
eISSN - 2042-3292
pISSN - 0957-7734
DOI - 10.1111/eve.12092
Subject(s) - medicine , horse , fasciculation , toxicity , agonist , hydrochloride , anesthesia , pharmacology , chemistry , receptor , biology , biochemistry , paleontology
Summary Zilpaterol hydrochloride is a β‐2 agonist utilised as a repartitioning agent in cattle. In recent years, it has also been used illicitly among human athletes and body builders, and administered to racehorses. While there are numerous anecdotal reports of the effects of zilpaterol in horses, this is the first documented clinical case of equine zilpaterol toxicity. The horse presented with marked tachycardia, profuse sweating and generalised muscle fasciculations. Ultimately, treatment was initiated with propranolol and the horse made a complete recovery.