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Pulmonary and hepatic eosinophilic granulomas and epistaxis in a horse suggestive of multi‐systemic eosinophilic epitheliotropic disease
Author(s) -
Horan E. M.,
Metcalfe L. V. A.,
Swarte M.,
Cahalan S. D.,
Katz L. M.
Publication year - 2013
Publication title -
equine veterinary education
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 31
eISSN - 2042-3292
pISSN - 0957-7734
DOI - 10.1111/eve.12017
Subject(s) - medicine , eosinophilic , pathology , lung , infiltration (hvac) , horse , eosinophilic granuloma , respiratory system , physics , thermodynamics , paleontology , biology
Summary Multi‐systemic eosinophilic epitheliotropic disease ( MEED ) is a relatively uncommon disease characterised by eosinophilic infiltration of more than one organ system, with the skin and gastrointestinal tract most commonly affected. This case report describes a gelding that presented for weight loss, increased respiratory rate and effort and chronic intermittent epistaxis. During post mortem examination diffuse eosinophilic granulomatous lesions were identified in the lung and liver, leading to a diagnosis of MEED . Veno‐occlusive pulmonary remodelling was also discovered, believed to be the cause of the chronic epistaxis and a result of the pulmonary fibrosis and eosinophilic granulomas.