PP 1/306 (1) General principles for the development of co‐formulated mixtures of plant protection products

Specific scope For the purpose of this Standard, a co‐formulated mixture[Note 1. Hereafter referred to as ‘mixture’ in this Standard. ...] is defined as a plant protection product which contains more than one active substance (including mixtures of different product types, e.g. fungicides plus insecticides or fungicides plus plant growth regulators). In certain cases, manufacturers may provide the individual active substances in separate containers in a common product package; these are usually referred to as ‘twin packs’ or ‘combi‐packs’. Such products are outside the scope of this Standard (although some of the same considerations apply for practical farm use). This Standard provides guidance for the justification for using mixtures from the point of view of efficacy, their potential advantages and disadvantages, plus an examination of the appropriateness of such mixtures in terms of managing resistance. Based on these issues, a series of principles have been drawn up to form the regulatory framework for the decision‐making process when considering the approval of such mixtures. These principles should also act as a guide for trial design and the type of data required. Appendices provide additional information for specific product types and situations. The Standard PP 1/277 Insecticide co‐formulated mixtures will be withdrawn and replaced by this new Standard. Specific approval and amendment First approved in 2018‐09.