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Harmonization in preclinical epilepsy research: A joint AES/ILAE translational initiative
Author(s) -
Galanopoulou Aristea S.,
French Jacqueline A.,
O'Brien Terence,
Simonato Michele
Publication year - 2017
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1111/epi.13921
Subject(s) - harmonization , preclinical research , translational research , task force , epilepsy , medicine , clinical research , research data , task (project management) , medical physics , psychiatry , political science , data science , computer science , pathology , engineering , systems engineering , data curation , physics , public administration , acoustics
Summary Among the priority next steps outlined during the first translational epilepsy research workshop in London, United Kingdom (2012), jointly organized by the American Epilepsy Society (AES) and the International League Against Epilepsy (ILAE), are the harmonization of research practices used in preclinical studies and the development of infrastructure that facilitates multicenter preclinical studies. The AES/ILAE Translational Task Force of the ILAE has been pursuing initiatives that advance these goals. In this supplement, we present the first reports of the working groups of the Task Force that aim to improve practices of performing rodent video–electroencephalography (vEEG) studies in experimental controls, generate systematic reviews of preclinical research data, and develop preclinical common data elements (CDEs) for epilepsy research in animals.